Article
Sex specificity, life-span QTLs, and statistical power.
The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Dec 2002
Curtsinger James W
Abstract excerpt
Most of the quantitative trait loci (QTLs) that have been found to influence life span in Drosophila and Mus organisms are reported to have genetic effects limited to one sex. Here I study the statistical properties of sex-limited QTLs by randomly sampling data from an exceptionally large Drosophila experiment, and then asking how sample size influences outcomes. The sampling study suggests that, for the...
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