Article
A genetic and genomic approach to identify longevity genes in mice.
Mechanisms of ageing and development - 1 Jan 2005
de Haan Gerald, Williams Robert W
Abstract excerpt
Natural variation in rate of aging or longevity in mice and humans shows a very complex inheritance pattern. Few targeted genetic screens have identified longevity genes in mammals, partly as a result from the fact that the genetics of longevity can only be studied reliably in cohorts of mice. In this paper we propose that a combined genetic and genomic analysis of large families of fully genotyped recombinant...
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