Article
Power calculations for selective genotyping in QTL mapping in backcross mice.
Genetical research - 1 Oct 2004
Rabbee Nusrat, Speca David, Armstrong Nicola J, Speed Terence P
Abstract excerpt
Selective genotyping concerns the genotyping of a portion of individuals chosen on the basis of their phenotypic values. Often individuals are selected for genotyping from the high and low extremes of the phenotypic distribution. This procedure yields savings in cost and time by decreasing the total number of individuals genotyped. Previous work by Darvasi et al. (1993) has shown that the power to detect a QTL by...
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