Article
Does caloric restriction extend life in wild mice?
Aging cell - 1 Dec 2006
Harper James M, Leathers Charles W, Austad Steven N
Abstract excerpt
To investigate whether mice genetically unaltered by many generations of laboratory selection exhibit similar hormonal and demographic responses to caloric restriction (CR) as laboratory rodents, we performed CR on cohorts of genetically heterogeneous male mice which were grandoffspring of wild-caught ancestors. Although hormonal changes, specifically an increase in corticosterone and decrease in testosterone,...
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