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Article

Crystallization and preliminary X-ray analysis of W120K mutant of streptavidin.

Acta crystallographica. Section D, Biological crystallography - 1 Dec 2001

Pazy Y, Laitinen O H, Ravoy B, Kulomaa M S, Wilchek M, Bayer E A, Livnah O

Abstract excerpt

Bacterial streptavidin and chicken avidin are homotetrameric proteins that share an exceptionally high affinity towards the vitamin biotin. The biotin-binding sites in both proteins contain a crucial tryptophan residue contributed from an adjacent subunit. This particular tryptophan (W110 in avidin and W120 in streptavidin) plays an important role in both biotin binding and in the quaternary stabilities of the...

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Identifiers

PMID: 11717505
DOI: 10.1107/s0907444901015141

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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