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Article

Homodimers of mutant tryptophan synthase alpha-subunits in Escherichia coli.

Biochemical and biophysical research communications - 30 Nov 2001

Kim J W, Kim E Y, Park H H, Jung J E, Kim H D, Shin H J, Lim W K

Abstract excerpt

Tryptophan synthase alpha-subunit from Escherichia coli functionally exists as a heterotetramer of alpha(2)beta(2) with beta-subunit. While wild-type and mutant (F139W, T24M/F139W, and T24L/F139W) alpha-subunits were expressed as a monomer from recombinant plasmids in Escherichia coli, T24A/F139W, T24S/F139W, and T24K/F139W mutant alpha-subunits were abnormally expressed as soluble homodimers in addition to...

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PMID: 11716512
DOI: 10.1006/bbrc.2001.6022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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