Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Aberrant growth plate development in VDR/RXR gamma double null mutant mice.

Endocrinology - 1 Dec 2001

Yagishita N, Yamamoto Y, Yoshizawa T, Sekine K, Uematsu Y, Murayama H, Nagai Y, Krezel W, Chambon P, Matsumoto T, Kato S

Abstract excerpt

VDR forms heterodimers with one of three RXRs, RXR alpha, RXR beta, and RXR gamma, and it is thought that RXR ligands can also modulate the trans-activation function of VDR/RXR heterodimers. In the present study we generated VDR/RXR gamma double null mutant mice to examine the convergent actions...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone and Bones
Share to Chondrocytes
Share to Growth Plate

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hypertrophy

Share to Minerals

Share to Osteoclasts

Share to Receptors, Retinoic Acid

Share to Retinoid X Receptors

Source

Identifiers

PMID: 11713233
DOI: 10.1210/endo.142.12.8544

Genes

VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11713233-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Aberrant growth plate development in VDR/RXR gamma double null mutant mice.PMID 11713233Read ↗

Coactivator-independent vitamin D receptor signaling causes severe rickets in mice, which is not prevented by a diet high in calcium, phosphate, and lactoseSemantic proximity Read ↗

Hypophosphatemia leads to rickets by impairing caspase-mediated apoptosis of hypertrophic chondrocytes.Semantic proximity Read ↗

Vitamin D and Human Health: Lessons from Vitamin D Receptor Null MiceSemantic proximity Read ↗

Role of the retinoic acid receptor beta (RARbeta) during mouse developmentSemantic proximity Read ↗

Vitamin D receptor in chondrocytes promotes osteoclastogenesis and regulates FGF23 production in osteoblasts.Semantic proximity Read ↗

Genetic analysis of RXR alpha developmental function: convergence of RXR and RAR signaling pathways in heart and eye morphogenesis.Semantic proximity Read ↗

Rescue of the skeletal phenotype of vitamin D receptor-ablated mice in the setting of normal mineral ion homeostasis: formal histomorphometric and biomechanical analyses.Semantic proximity Read ↗

Sex-related differences in the skeletal phenotype of aged vitamin D receptor global knockout mice.Semantic proximity Read ↗

Physiopathology of dental rickets in vitamin D receptor-ablated mice.Semantic proximity Read ↗

Nongenomic effects of 1α,25-dihydroxyvitamin D3 on cartilage formation deduced from comparisons between Cyp27b1 and Vdr knockout mice.Semantic proximity Read ↗

Limited specificity and large overlap of the functions of the mouse RAR gamma 1 and RAR gamma 2 isoforms.Semantic proximity Read ↗

Coordinated tether formation in anatomically distinct mice growth centers is dependent on a functional vitamin D receptor and is tightly linked to three-dimensional tissue morphology.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.