Article
Primary liver carcinoma in genetic hemochromatosis reveals a broad histologic spectrum.
American journal of clinical pathology - 1 Nov 2001
Morcos M, Dubois S, Bralet M P, Belghiti J, Degott C, Terris B
Abstract excerpt
Hepatocellular carcinoma (HCC) is a well-known complication of genetic hemochromatosis (GH). However, the frequency of primary liver carcinoma (PLC) with biliary differentiation, such as cholangiocarcinoma (CC) and combined hepatocholangiocarcinoma (CHCC), in GH remains unclear We analyzed the histologic type of 20 PLCs occurring in the background of GH; all patients were homozygotic for the C282Y mutation. Ten...
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