Article
Expression of both hepatocellular carcinoma and cholangiocarcinoma phenotypes in hepatocellular carcinoma and cholangiocarcinoma components in combined hepatocellular and cholangiocarcinoma.
Medical molecular morphology - 1 Dec 2012
Itoyama Mitsumaro, Hata Masaki, Yamanegi Koji, Yamada Naoko, Ohyama Hideki, Hirano Hiroshi, Terada Nobuyuki, Nakasho Keiji
Abstract excerpt
Expression of phenotype markers of hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC) in HCC and CC components of 20 combined hepatocellular and cholangiocarcinomas (CHCs) of the liver was investigated immunohistochemically. Both HCC and CC components of all CHCs expressed at least one of the CC phenotype markers [cytokeratin (CK)-7, CK-19, and carbohydrate (CA) 19-9]. HCC components in 90% of CHCs and CC...
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