Article
Can large cell change and high proliferative activity predict hepatocellular carcinoma in patients with hereditary hemochromatosis?
The American journal of gastroenterology - 1 Oct 2000
Fracanzani A L, Borzio M, Roncalli M, Derenzini M, Trerè D, Mattioli M, Taioli E, Fiorelli G, Fargion S
Abstract excerpt
OBJECTIVE: Patients with hereditary hemochromatosis are at high risk of developing hepatocellular carcinoma. This study was undertaken to define whether large cell change and nucleolar organizer regions proliferative index (marker of high proliferative activity) predict hepatocellular carcinoma development in hereditary hemochromatosis. METHODS: Histological staining for large cell change and high proliferative...
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