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Article

Strong HLA class I--restricted T cell responses in dengue hemorrhagic fever: a double-edged sword?

The Journal of infectious diseases - 1 Dec 2001

Loke H, Bethell D B, Phuong C X, Dung M, Schneider J, White N J, Day N P, Farrar J, Hill A V

Abstract excerpt

Dengue is an increasingly important cause of morbidity and mortality in the tropics, but vaccine development has been impeded by a poor understanding of disease pathogenesis and, in particular, of immunologic enhancement. In a large case-control study of Vietnamese patients with dengue hemorrhagic fever (DHF), variation at the HLA-A locus was significantly associated with susceptibility to DHF (P=.02), and...

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Share to Antigens, Viral
Share to CD8-Positive T-Lymphocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11709777
DOI: 10.1086/324320

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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