Article
Interleukin 16 expression and phenotype of interleukin 16 producing cells in Crohn's disease.
Gut - 1 Dec 2001
Middel P, Reich K, Polzien F, Blaschke V, Hemmerlein B, Herms J, Korabiowska M, Radzun H J
Abstract excerpt
BACKGROUND: The mechanisms involved in the initiation and maintenance of Crohn's disease are poorly understood. Previous studies have demonstrated an increased number of infiltrating CD4+ T cells within the inflammatory affected bowel wall in Crohn's disease. Novel therapy approaches using anti-CD4 antibodies are thought to be effective in Crohn's disease. AIMS: Interleukin 16 (IL-16) has been characterised as a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
