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Thromboxane A2 Signalling in Humans: a ‘Tail’ of Two Receptors

1 Nov 2001

Abstract excerpt

Since its discovery in 1975, we now have a wealth of knowledge relating to the biochemical, pharmacological and physiological actions of thromboxane A(2) (TXA(2)) and its related metabolites. These molecular insights have been greatly expedited by the molecular cloning and characterization of a cDNA for the human TXA(2) receptor, now termed the T Prostanoid or TP receptor, from a megakaryocytic/placental cDNA...

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PMID: 11709048
DOI: 10.1042/bst0290641

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