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Insights into the Expression, Structure, and Function of the Thromboxane A2 Receptor in Vascular Biology

11 Aug 2025

Abstract excerpt

The thromboxane A 2 receptor is known for its role in platelet aggregation. In platelets, loss or gain-of-function of the thromboxane A 2 receptor may therefore lead to bleeding disorders or prothrombotic conditions. However, the thromboxane A 2 receptor is also expressed in many other cell types and tissues and is thought to contribute to a broad range of other pathophysiological processes, such as pulmonary...

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PMID: 40969894
DOI: 10.1021/acsptsci.5c00378

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