Article
Virulence of Leishmania infantum is expressed as a clonal and dominant phenotype in experimental infections.
Infection and immunity - 1 Dec 2001
Garin Y J, Sulahian A, Pratlong F, Meneceur P, Gangneux J P, Prina E, Dedet J P, Derouin F
Abstract excerpt
Human Leishmania infantum infection results in a spectrum of clinical expressions ranging from cutaneous to either asymptomatic or fatal visceral disease. In this context, characterization of parasite virulence appears to be relevant as a biological marker of intrinsic parasitic factors that can affect the pathology of leishmaniasis. Since parasite populations in naturally infected hosts are likely to be composed...
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