Article
Studies in the mouse model identify strain variability as a major determinant of disease outcome in Leishmania infantum infection.
Parasites & vectors - 18 Dec 2015
Marques Filipe, Vale-Costa Sílvia, Cruz Tânia, Marques Joana Moreira, Silva Tânia, Neves João Vilares, Cortes Sofia, Fernandes Ana, Rocha Eduardo, Appelberg Rui, Rodrigues Pedro, Tomás Ana M, Gomes Maria Salomé
Abstract excerpt
BACKGROUND: Visceral leishmaniasis is a severe and potentially fatal disease caused by protozoa of the genus Leishmania, transmitted by phlebotomine sandflies. In Europe and the Mediterranean region, L. infantum is the commonest agent of visceral leishmaniasis, causing a wide spectrum of clinical manifestations, including asymptomatic carriage, cutaneous lesions and severe visceral disease. Visceral leishmaniasis...
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