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WITHIN-HOST COMPETITION IN GENETICALLY DIVERSE MALARIA INFECTIONS: PARASITE VIRULENCE AND COMPETITIVE SUCCESS

1 Jul 2006

Abstract excerpt

Humans and animals often become coinfected with pathogen strains that differ in virulence. The ensuing interaction between these strains can, in theory, be a major determinant of the direction of selection on virulence genes in pathogen populations. Many mathematical analyses of this assume that virulent pathogen lineages have a competitive advantage within coinfected hosts and thus predict that pathogens will...

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PMID: 16929653
DOI: 10.1111/j.0014-3820.2006.tb01215.x

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