Article
Antimalarial antibody levels and IL4 polymorphism in the Fulani of West Africa.
Genes and immunity - 1 Nov 2001
Luoni G, Verra F, Arcà B, Sirima B S, Troye-Blomberg M, Coluzzi M, Kwiatkowski D, Modiano D
Abstract excerpt
The Fulani are less clinically susceptible and more immunologically responsive to malaria than neighbouring ethnic groups. Here we report that anti-malarial antibody levels show a wide distribution amongst the Fulani themselves, raising the possibility that quantitative analysis within the Fulani may be an efficient way of screening for important genetic factors. The Th2 cytokine interleukin-4 is an obvious...
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