Article
Ethnic differences in susceptibility to malaria: what have we learned from immuno-epidemiological studies in West Africa?
Acta tropica - 1 Jun 2015
Arama Charles, Maiga Bakary, Dolo Amagana, Kouriba Bourèma, Traoré Boubacar, Crompton Peter D, Pierce Susan K, Troye-Blomberg Marita, Miller Louis H, Doumbo Ogobara K
Abstract excerpt
There are many fundamental aspects of the immunobiology of Plasmodium falciparum infections that are not fully understood, therefore limiting our comprehension of how people become immune to malaria and why some ethnic groups living in malaria endemic areas are less susceptible than others. The complexity of parasite-host interactions and the genetic diversity of the parasites as well as the human host complicate...
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