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Article

IL4 gene polymorphism and previous malaria experiences manipulate anti-Plasmodium falciparum antibody isotype profiles in complicated and uncomplicated malaria.

Malaria journal - 10 Dec 2009

Tangteerawatana Piyatida, Perlmann Hedvig, Hayano Masashi, Kalambaheti Thareerat, Troye-Blomberg Marita, Khusmith Srisin

Abstract excerpt

BACKGROUND: The IL4-590 gene polymorphism has been shown to be associated with elevated levels of anti-Plasmodium falciparum IgG antibodies and parasite intensity in the malaria protected Fulani of West Africa. This study aimed to investigate the possible impact of IL4-590C/T polymorphism on anti-P. falciparum IgG subclasses and IgE antibodies levels and the alteration of malaria severity in complicated and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20003246
DOI: 10.1186/1475-2875-8-286
PMCID: PMC2799430

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