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Article

Structural and functional role of threonine 112 in a superantigen Staphylococcus aureus enterotoxin B.

The Journal of biological chemistry - 25 Jan 2002

Baker Matthew D, Papageorgiou Anastassios C, Titball Richard W, Miller Julie, White Sarah, Lingard Bryan, Lee Jeong Jin, Cavanagh David, Kehoe Michael A, Robinson John H, Acharya K Ravi

Abstract excerpt

Bacterial superantigens are potent T-cell stimulatory protein molecules produced by Staphylococcus aureus and Streptococcus pyogenes. Their superantigenic activity can be attributed to their ability to cross-link major histocompatibility complex class II molecules with T-cell receptors (TCRs) to form a tri-molecular complex. Each superantigen is known to interact with a specific V(beta) element of TCR....

Read the complete abstract on PubMed

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Share to Amino Acids
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genes, MHC Class II

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Share to Microscopy, Fluorescence

Share to Receptors, Antigen, T-Cell, alpha-beta

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Source

Identifiers

PMID: 11704673
DOI: 10.1074/jbc.M109369200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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