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Article

Enhanced exercise-induced GH secretion in subjects with Pro7 substitution in the prepro-NPY.

The Journal of clinical endocrinology and metabolism - 1 Nov 2001

Kallio J, Pesonen U, Karvonen M K, Kojima M, Hosoda H, Kangawa K, Koulu M

Abstract excerpt

The leucine 7 to proline 7 (Leu7Pro) polymorphism in the signal peptide of NPY is associated with high blood lipid concentrations and accelerated rate of atherosclerosis as well as diabetic retinopathy. Also, healthy subjects with this polymorphism have increased NPY secretion during sympathetic stimulation. Because NPY may regulate GH release and ghrelin may regulate NPY formation, we studied the effects of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11701704
DOI: 10.1210/jcem.86.11.7977

Genes

NPY

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Enhanced exercise-induced GH secretion in subjects with Pro7 substitution in the prepro-NPY.PMID 11701704Read ↗

Changes in diurnal sympathoadrenal balance and pituitary hormone secretion in subjects with Leu7Pro polymorphism in the prepro-neuropeptide Y.Semantic proximity Read ↗

The Leu7Pro polymorphism of preproNPY is associated with decreased insulin secretion, delayed ghrelin suppression, and increased cardiovascular responsiveness to norepinephrine during oral glucose tolerance test.Semantic proximity Read ↗

Association of a leucine(7)-to-proline(7) polymorphism in the signal peptide of neuropeptide Y with high serum cholesterol and LDL cholesterol levels.Semantic proximity Read ↗

Enhanced endothelium-dependent vasodilation in subjects with Proline7 substitution in the signal peptide of neuropeptide Y.Semantic proximity Read ↗

The impact of the leucine 7 to proline 7 polymorphism of the neuropeptide Y gene on postprandial lipemia and on the response of serum total and lipoprotein lipids to a reduced fat diet.Semantic proximity Read ↗

A leucine(7)-to-proline(7) polymorphism in the signal peptide of neuropeptide Y was not identified in the Japanese population.Semantic proximity Read ↗

Leucine7 to proline7 polymorphism in the preproneuropeptide Y is associated with the progression of carotid atherosclerosis, blood pressure and serum lipids in Finnish menSemantic proximity Read ↗

Leu7Pro polymorphism in the neuropeptide Y (NPY) gene is associated with impaired glucose tolerance and type 2 diabetes in Swedish men.Semantic proximity Read ↗

Leucine 7 to proline 7 polymorphism in the neuropeptide Y gene is associated with enhanced carotid atherosclerosis in elderly patients with type 2 diabetes and control subjects.Semantic proximity Read ↗

Altered intracellular processing and release of neuropeptide Y due to leucine 7 to proline 7 polymorphism in the signal peptide of preproneuropeptide Y in humans.Semantic proximity Read ↗

The Leu7Pro polymorphism of the neuropeptide Y gene regulates free fatty acid metabolism.Semantic proximity Read ↗

Nutrient intake, weight, and Leu7Pro polymorphism in prepro-neuropeptide Y in children.Semantic proximity Read ↗

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