Article
A leucine(7)-to-proline(7) polymorphism in the signal peptide of neuropeptide Y was not identified in the Japanese population.
Journal of clinical pharmacy and therapeutics - 1 Jun 2001
Makino K, Kataoka Y, Hirakawa Y, Ikeda A, Yamauchi A, Oishi A R
Abstract excerpt
OBJECTIVE: A Leu(7)-to-Pro(7) polymorphism exists in the signal peptide part of prepro-neuropeptide Y (NPY) and this polymorphism is associated with high serum cholesterol and LDL cholesterol levels in both Finnish and Dutch people. There was a significant difference in the allelic frequencies among populations with different genetic backgrounds. Therefore, the present study was designed to test whether Japanese...
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