Article
Olanzapine disposition in humans is unrelated to CYP1A2 and CYP2D6 phenotypes.
European journal of clinical pharmacology - 1 Sept 2001
Hägg S, Spigset O, Lakso H A, Dahlqvist R
Abstract excerpt
OBJECTIVE: Limited data suggest that CYP1A2 and CYP2D6 are involved in the metabolism of olanzapine. The purpose of this study was to further elucidate the role of these enzymes in the disposition of olanzapine in vivo. METHODS: Seventeen healthy non-smoking male volunteers were included in the s...
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