Article
Considering CYP1A2 phenotype and genotype for optimizing the dose of olanzapine in the management of schizophrenia.
Expert opinion on drug metabolism & toxicology - 1 Sept 2013
Perera Vidya, Gross Annette S, Polasek Thomas M, Qin Yan, Rao Gauri, Forrest Alan, Xu Junzhe, McLachlan Andrew J
Abstract excerpt
INTRODUCTION: Schizophrenia, a mental disorder, is a debilitating condition which typically strikes young people in their early 20's. Antipsychotic medications are widely prescribed for the treatment of schizophrenia however a balancing act is necessary to provide the correct dose to each patient. It is suggested that a large number of patients discontinue antipsychotic pharmacotherapy because the treatments...
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