Article
Analysis of the CHK2 gene in lymphoid malignancies.
Leukemia & lymphoma - 1 Jul 2001
Tavor S, Takeuchi S, Tsukasaki K, Miller C W, Hofmann W K, Ikezoe T, Said J W, Koeffler H P
Abstract excerpt
The CHK2 gene encodes a protein kinase that is important for the regulation of cell cycle arrest after DNA damage. CHK2 acts downstream of ataxia teleangiecstasia mutated (ATM), modulates the function of p53 and may help mediate cell cycle arrest at G2/M by phosphorylation of Cdc25C. Recently, th...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
