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Article

Direct comparison of detection systems used for the development of single-cell genetic tests in preimplantation genetic diagnosis.

Journal of assisted reproduction and genetics - 1 Oct 2001

Blake D L, Dean N L, Knight C, Tan S L, Ao A

Abstract excerpt

PURPOSE: Single-cell polymerase chain reaction (PCR) requires efficient amplification and accurate detection. We compare the accuracy of heteroduplex, fluorescent-fragment, and fluorescent single-strand conformation polymorphism (F-SSCP) analysis as detection systems for analysis of a PCR assay developed for preimplantation genetic diagnosis. METHODS: A single-cell, fluorescent multiplex PCR assay was developed...

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Identifiers

PMID: 11699128
DOI: 10.1023/a:1011958008240
PMCID: PMC3455313

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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