Article
Failure of combination therapy with lamivudine and famciclovir following lamivudine monotherapy for hepatitis B virus infection in patients coinfected with human immunodeficiency virus-1.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 15 Dec 2001
Matthews G V, Pillay D, Cane P, Ratcliffe D, Gazzard B, Nelson M
Abstract excerpt
Individuals coinfected with human immunodeficiency virus 1 (HIV-1) and hepatitis B virus (HBV) often receive treatment with an antiretroviral regimen including lamivudine. Lamivudine monotherapy for HBV may lead to drug-resistant mutations in a significant number of patients. The virological and biochemical responses of 8 patients coinfected with HBV/HIV-1 treated with both lamivudine and famciclovir were...
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