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Article

IL-13 in asthma and allergic disease: asthma phenotypes and targeted therapies.

The Journal of allergy and clinical immunology - 1 Oct 2012

Ingram Jennifer L, Kraft Monica

Abstract excerpt

Decades of research in animal models have provided abundant evidence to show that IL-13 is a key T(H)2 cytokine that directs many of the important features of airway inflammation and remodeling in patients with allergic asthma. Several promising focused therapies for asthma that target the IL-13/IL-4/signal transducer and activator of transcription 6 pathway are in development, including anti-IL-13 mAbs and IL-4...

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Source

Identifiers

PMID: 22951057
DOI: 10.1016/j.jaci.2012.06.034

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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