Article
Transient disruption of spermatogenesis by deregulated expression of neurturin in testis.
Molecular and cellular endocrinology - 26 Nov 2001
Meng X, Pata I, Pedrono E, Popsueva A, de Rooij D G, Jänne M, Rauvala H, Sariola H
Abstract excerpt
Two related ligands, glial cell line-derived neurotrophic factor (GDNF) and neurturin (NRTN), are expressed by Sertoli cells, but their cognate ligand-binding co-receptors, GDNF family receptor alpha1 and alpha2, are displayed by different germ cells suggesting different targets for the ligands. GDNF regulates cell fate decision of undifferentiated spermatogonia 'Science 287 (2000) 1489'. The role of NRTN was now...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
