Article
Snail family genes are required for left-right asymmetry determination, but not neural crest formation, in mice.
Proceedings of the National Academy of Sciences of the United States of America - 5 Jul 2006
Murray Stephen A, Gridley Thomas
Abstract excerpt
Snail family genes encode zinc finger transcriptional repressors that are key regulators of epithelial-mesenchymal transitions in vertebrates, including the transitions that generate the mesoderm and neural crest. Here, we show that, contrary to observations in frog and avian embryos, the Snail family genes Snail (Snai1) and Slug (Snai2) are not required for formation and delamination of the neural crest in mice....
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