Article
Conserved Wat1/Pop3 WD-repeat protein of fission yeast secures genome stability through microtubule integrity and may be involved in mRNA maturation.
Journal of cell science - 1 Aug 2001
Ochotorena I L, Hirata D, Kominami K, Potashkin J, Sahin F, Wentz-Hunter K, Gould K L, Sato K, Yoshida Y, Vardy L, Toda T
Abstract excerpt
Accurate chromosome segregation is dependent upon the integrity of mitotic spindles, which pull each pair of sister chromatids towards opposite poles. In this study, we have characterised fission yeast pop3-5235, a diploidising mutant that is impaired in genome stability. Pop3 is the same as Wat1, a conserved protein containing 7 WD repeats. Pop3/Wat1 has also been isolated from a two-hybrid screen as a binding...
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