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Article

UV-induced DNA damage, repair, mutations and oncogenic pathways in skin cancer.

Journal of photochemistry and photobiology. B, Biology - 1 Oct 2001

de Gruijl F R, van Kranen H J, Mullenders L H

Abstract excerpt

Repair of UV induced DNA damage is of key importance to UV-induced skin carcinogenesis. Specific signal transduction pathways that regulate cell cycling, differentiation and apoptosis are found to be corrupted in skin cancers, e.g., the epidermal growth-stimulating Hedgehog pathway in basal cell carcinomas (BCCs). Mutations in genes coding for proteins in these pathways lead to persistent disturbances that are...

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Identifiers

PMID: 11684448
DOI: 10.1016/s1011-1344(01)00199-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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