Article
The molecular pathways of ultraviolet-induced carcinogenesis.
Mutation research - 16 Jul 1999
Sarasin A
Abstract excerpt
Cancer development requires the accumulation of numerous genetic changes which are usually believed to occur through the presence of unrepaired DNA lesions. Exogenous or endogenous DNA-damaging agents can lead to mutations in the absence of efficient error-free repair, via replication of DNA damage. Several DNA repair pathways are present in living cells and well-conserved from bacteria to human cells. The...
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