Article

UV damage, DNA repair and skin carcinogenesis

2002-01-01

Abstract excerpt

Skin cancer is unique among human cancers in its etiology, accessibility and the volume of detailed knowledge now assembled concerning its molecular mechanisms of origin. The major carcinogenic agent for most skin cancers is well established as solar ultraviolet light. This is absorbed in DNA with the formation of UV-specific dipyrimidine photoproducts. These can be repaired by nucleotide excision repair or replic...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0cdd128a-0377-5e9f-9ca9-33c21b201602
DOI: 10.2741/cleaver

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

UV damage, DNA repair and skin carcinogenesisDOI 10.2741/cleaverRead

Deciphering UV‐induced DNA Damage Responses to Prevent and Treat Skin CancerSemantic proximity Read

Mechanisms of UV-induced mutations and skin cancerSemantic proximity Read

The Interdependence of Skin Aging, Skin Cancer, and DNA Repair Capacity: A Novel Perspective with Therapeutic ImplicationsSemantic proximity Read

Short-term and long-term cellular and molecular events following UV irradiation of skin: implications for molecular medicineSemantic proximity Read

Skin Photodamage and Melanomagenesis: A Comprehensive ReviewSemantic proximity Read

Skin cancer: role of ultraviolet radiation in carcinogenesisSemantic proximity Read

Oxidative Stress and Genotoxicity in Melanoma Induction: Impact on Repair Rather Than Formation of DNA Damage?Semantic proximity Read

UVA Radiation, DNA Damage, and MelanomaSemantic proximity Read

Mechanism of UV-related carcinogenesis and its contribution to nevi/melanomaSemantic proximity Read

Genome-wide profiles of UV lesion susceptibility, repair, and mutagenic potential in melanoma.Semantic proximity Read

Further assessment of exome-wide UVR footprints in melanoma and their possible relevance.Semantic proximity Read

The role of sunlight and DNA repair in melanoma and nonmelanoma skin cancer. The xeroderma pigmentosum paradigmSemantic proximity Read