Article
Emerging roles for chromatin remodeling in cancer biology.
Trends in cell biology - 1 Nov 2001
Cairns B R
Abstract excerpt
Cell proliferation and differentiation are guided by changes in gene expression and require the coordinated efforts of the transcription machinery and chromatin-remodeling factors. However, aberrant regulation of chromatin structure can arise through mutations in chromatin-modifying and -remodeling proteins and can lead to improper gene expression and cancer. This review discusses how mutations in chromatin...
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