Article
Cell-autonomous and -nonautonomous functions of LAR in R7 photoreceptor axon targeting.
Neuron - 25 Oct 2001
Maurel-Zaffran C, Suzuki T, Gahmon G, Treisman J E, Dickson B J
Abstract excerpt
During Drosophila visual system development, photoreceptors R7 and R8 project axons to targets in distinct layers of the optic lobe. We show here that the LAR receptor tyrosine phosphatase is required in the eye for correct targeting of R7 axons. In LAR mutants, R7 axons initially project to their correct target layer, but then retract to the R8 target layer. This targeting defect can be fully rescued by...
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