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Article

Retinal axon target selection in Drosophila is regulated by a receptor protein tyrosine phosphatase.

Neuron - 1 Apr 1999

Garrity P A, Lee C H, Salecker I, Robertson H C, Desai C J, Zinn K, Zipursky S L

Abstract excerpt

Different Drosophila photoreceptors (R cells) connect to neurons in different optic lobe layers. R1-R6 axons project to the lamina; R7 and R8 axons project to separate layers of the medulla. We show a receptor tyrosine phosphatase, PTP69D, is required for lamina target specificity. In Ptp69D mutants, R1-R6 project through the lamina, terminating in the medulla. Genetic mosaics, transgene rescue, and...

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Source

Identifiers

PMID: 10230791
DOI: 10.1016/s0896-6273(00)80730-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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