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Article

Anions stabilize a metarhodopsin II-like photoproduct with a protonated Schiff base.

Biochemistry - 6 Nov 2001

Vogel R, Fan G B, Siebert F, Sheves M

Abstract excerpt

In rhodopsin, the retinal chromophore is covalently bound to the apoprotein by a protonated Schiff base, which is stabilized by the negatively charged counterion Glu113, conferring upon it a pK(a) of presumably >16. Upon photoexcitation and conformational relaxation of the initial photoproducts, the Schiff base proton neutralizes the counterion, a step that is considered a prerequisite for formation of the active...

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Identifiers

PMID: 11683644
DOI: 10.1021/bi0113667

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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