Article
Cell cycle attenuation by p120E4F is accompanied by increased mitotic dysfunction.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research - 1 Oct 2001
Rooney R J
Abstract excerpt
In addition to their well-established roles at the G1-S checkpoint, recent reports support a role for universal cyclin-dependent kinase (CDK) inhibitors in the control of G2-M and suggest that their induction may stimulate the occurrence of endomitosis or polyploidy in a number of physiological settings. In this report, the stable expression of the p120E4F transcription factor, which attenuates G1-S progression...
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