Dimerization of the 3'UTR of bicoid mRNA involves a two-step mechanism.

doi:10.1006/jmbi.2001.5057

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Article

Dimerization of the 3'UTR of bicoid mRNA involves a two-step mechanism.

Journal of molecular biology - 26 Oct 2001

Wagner C, Palacios I, Jaeger L, St Johnston D, Ehresmann B, Ehresmann C, Brunel C

Abstract excerpt

The proper localization of bicoid (bcd) mRNA requires cis-acting signals within its 3' untranslated region (UTR) and trans-acting factors such as Staufen. Dimerization of bcd mRNA through intermolecular base-pairing between two complementary loops of domain III of the 3'UTR was proposed to be important for particle formation in the embryo. The participation in the dimerization process of each domain building the...

Topics

3' Untranslated Regions
Animals
Base Pairing
Base Sequence
Biological Transport
Dimerization
Drosophila Proteins
Drosophila melanogaster
Genes, Insect
Homeodomain Proteins
Kinetics
Models, Biological
Mutation
Nucleic Acid Conformation

Source

Open in PubMed

Identifiers

PMID: 11676536
DOI: 10.1006/jmbi.2001.5057

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Oligonucleotides

Protein Transport

RNA-Binding Proteins

Regulatory Sequences, Nucleic Acid