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Article

Autonomous determination of anterior structures in the early Drosophila embryo by the bicoid morphogen.

Development (Cambridge, England) - 1 Aug 1990

Driever W, Siegel V, Nüsslein-Volhard C

Abstract excerpt

A small number of maternal effect genes determine anterior-posterior pattern in the Drosophila embryo. Embryos from females mutant for the maternal gene bicoid lack head and thorax. bcd mRNA becomes localized to the anterior tip of the egg during oogenesis and is the source for the morphogen gradient of bcd protein. Here we show that in vitro transcribed bicoid mRNA that has its own leader sequences substituted...

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Identifiers

PMID: 2226200
DOI: 10.1242/dev.109.4.811

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Autonomous determination of anterior structures in the early Drosophila embryo by the bicoid morphogen.PMID 2226200Read ↗

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