Article
Leptin resistance is associated with extreme obesity and aggregates in families.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity - 1 Oct 2001
Lee J H, Reed D R, Price R A
Abstract excerpt
OBJECTIVE: To examine the determinants of plasma leptin levels and leptin resistance in a sample of extremely obese subjects and their relatives. DESIGN AND METHOD: We obtained plasma leptin values on 968 individuals from 218 families having both extremely obese and average weight members for obesity related variables. Multivariate regression analyses were used to identify predictors of both plasma leptin...
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