Article
Elevated plasma adiponectin in humans with genetically defective insulin receptors.
The Journal of clinical endocrinology and metabolism - 1 Aug 2006
Semple R K, Soos M A, Luan J, Mitchell C S, Wilson J C, Gurnell M, Cochran E K, Gorden P, Chatterjee V K K, Wareham N J, O'Rahilly S
Abstract excerpt
CONTEXT: Adiponectin has been suggested to play a role in the etiopathogenesis of at least some forms of insulin resistance, in part based on a strong correlation between plasma levels of adiponectin and measures of insulin sensitivity. OBJECTIVE: The objective of the study was to establish whether this relationship is maintained at extreme levels of insulin resistance. DESIGN/SETTING: This was a cross-sectional...
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