Article
Analysis of the human progesterone receptor gene polymorphism progins in Austrian ovarian carcinoma patients.
International journal of cancer - 20 Nov 2001
Tong D, Fabjani G, Heinze G, Obermair A, Leodolter S, Zeillinger R
Abstract excerpt
Ovarian carcinoma is the highest death cause in gynecologic malignancies. Although the molecular basis for familial breast and ovarian cancer is elucidated, few genetic markers have been associated with sporadic ovarian carcinoma. A polymorphism in intron G of the human progesterone receptor (PgR), caused by an Alu insertion, was described to be associated with ovarian carcinoma in a pooled German/Irish...
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