Article
Molecular determination of progesterone receptor's PROGINS allele (Alu insertion) and its association with the predisposition and susceptibility to polycystic ovary syndrome (PCOS).
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Sept 2022
Mir Rashid, Altayar Malik A, Hamadi Abdullah, Tayeb Faris J, Saeedi Nizar H, Jalal Mohammed M, Barnawi Jameel, Alshammari Sanad E, Mtiraoui Nabil, Ali Mohammed Eltigani M, Abuduhier Faisel M, Ullah Mohammad Fahad
Abstract excerpt
Polycystic ovary syndrome, previously known as Stein-Leventhal syndrome, is associated with altered reproductive endocrinology, predisposing a young woman towards the risk of PCOS. It has a prevalence of 6-20% among the reproductive-age women. Progesterone is a key hormone in the pathophysiology of PCOS and patients show diminished response (progesterone resistance), implicating the role of progesterone receptor...
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