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Article

Clarifying the PROGINS allele association in ovarian and breast cancer risk: a haplotype-based analysis.

Journal of the National Cancer Institute - 5 Jan 2005

Pearce Celeste Leigh, Hirschhorn Joel N, Wu Anna H, Burtt Noël P, Stram Daniel O, Young Stanton, Kolonel Laurence N, Henderson Brian E, Altshuler David, Pike Malcolm C

Abstract excerpt

BACKGROUND: The PROGINS allele of the progesterone receptor (PGR) gene has been associated with an increased risk of ovarian cancer and a decreased risk of breast cancer. We set out to refine the association between common variation at the PGR gene locus and these two diseases. METHODS: We characterized the haplotype structure of the PGR gene by genotyping 54 single-nucleotide polymorphisms (SNPs) in 349 women....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15632380
DOI: 10.1093/jnci/dji007

Genes

PGR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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