Article
Gamma-radiation sensitivity and risk of glioma.
Journal of the National Cancer Institute - 17 Oct 2001
Bondy M L, Wang L E, El-Zein R, de Andrade M, Selvan M S, Bruner J M, Levin V A, Alfred Yung W K, Adatto P, Wei Q
Abstract excerpt
BACKGROUND: About 9% of human cancers are brain tumors, of which 90% are gliomas. gamma-Radiation has been identified as a risk factor for brain tumors. In a previous pilot study, we found that lymphocytes from patients with glioma were more sensitive to gamma-radiation than were lymphocytes from matched control subjects. In this larger case-control study, we compared the gamma-radiation sensitivity of...
Topics
- Adult
- Animals
- Brain Neoplasms
- Case-Control Studies
- Chromatids
- Chromosome Breakage
- DNA
- DNA Damage
- DNA Repair
- DNA, Single-Stranded
- Demecolcine
- Female
- Gamma Rays
- Genetic Predisposition to Disease
- Glioma
