Article
SUMO modification of Rad22, the Schizosaccharomyces pombe homologue of the recombination protein Rad52.
Nucleic acids research - 15 Oct 2001
Ho J C, Warr N J, Shimizu H, Watts F Z
Abstract excerpt
The Schizosaccharomyces pombe rad31 and hus5 genes are required for the DNA damage response, as mutants defective in these genes are sensitive to DNA damaging agents, such as UV and ionising radiation and to the DNA synthesis inhibitor hydroxyurea (HU). Sequence analysis has suggested that rad31 and hus5 encode components of the Pmt3 (SUMO) modification process in S.pombe. We show here that the rad31 null and...
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