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Article

Experimental verification of the 'stability profile of mutant protein' (SPMP) data using mutant human lysozymes.

Protein engineering - 1 Aug 1999

Takano K, Ota M, Ogasahara K, Yamagata Y, Nishikawa K, Yutani K

Abstract excerpt

The stability profile of mutant protein (SPMP) (Ota,M., Kanaya,S. and Nishikawa,K., 1995, J. Mol. Biol., 248, 733-738) estimates the changes in conformational stability due to single amino acid substitutions using a pseudo-energy potential developed for evaluating structure-sequence compatibility in the structure prediction method, the 3D-1D compatibility evaluation. Nine mutant human lysozymes expected to...

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PMID: 10469827
DOI: 10.1093/protein/12.8.663

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